Description

AZAdvances Internships are designed to support students as they explore career paths in health and life sciences.

AZAdvances is part of the Opportunity Through Entrepreneurship Foundation.

Summary of the Company: 

Microvascular Therapeutics (MVT) is a biotechnology company specializing in the development of microbubble and nanotechnology products that will unlock the diagnostic and therapeutic potential of ultrasound.  MVT has invented a new ultrasound contrast agent, CardiSon (MVT-100), which promises to be the best combination of image quality, storage/handling, and side-effect prole of any ultrasound contrast agent on the market. CardiSon is being developed via the 505(B)1 regulatory pathway and has finished Phase 2 clinical testing for echocardiography. The projected approval date is Q4 2027. CardiSon is a near-term revenue opportunity, and a platform technology, that positions MVT to propel a pipeline of disruptive therapeutic products into the market that will have a broad impact across a spectrum of medicines, with massive market potential.

Description of the project: 

CardiSon is a product based on its predicate, Perflutren Lipid Microspheres.  To activate the bubbles for their use, the vial of solution requires activation using the “VialMix”.  The project is to further engineer the new shaker “CardiMix” and characterize the parameters for the activation of CardiSon using the shaker.  Another part of the project is to formulate innovative microbubbles with various gases for therapeutic indications.  

Compensation: 

This is a 3-month internship position. The intern will work 20 hours per week and compensation is 17.31 per hour ($750.00 twice per month). The intern will be hired by the Opportunity Through Entrepreneurship Foundation and perform their internship duties at Microvascular Therapeutics’ Tucson, AZ location.

Equal Opportunity:

The Opportunity Through Entrepreneurship Foundation recruits, hires, develops, and promotes employees based on the individual’s ability and job performance. This policy of nondiscrimination on the basis of race, sex, sexual orientation, gender identity, religion, national origin, color, age, disability, or any other status protected by federal or state law extends to all conditions and all areas of the workplace. Hiring decisions, promotions, training, pay, benefits, layoffs, terminations, in fact, all personnel actions, are covered by this policy.

Contacts: 

Microvascular Therapeutics:

Emmanuelle Meuillet, PhD

1635 E 18th street, Tucson AZ 85719

(520)730-3264 or e.meuillet@mvtpharma.com

AZAdvances:

Dylan Peay, PhD

850 N. 5th St., Phoenix, AZ 85004

Email: dylan@azadvances.org m: (484)362-4768

Requirements

Responsibilities:

You will be performing a set of experiments and measure the specifications of the product using several instrumentations such as GC/Raman, HPLC, DLS etc.  The measurement of the backscatter coefficient and Mechanical Index (MI) of the generated bubbles will also be a determined parameter.  You will be involved in the design and testing the hypothesis to the analyses for your data.  

The Intern will report to company mentors:  Dr Joel Lusk and Dr. Emmanuelle Meuillet.  A final report will be submitted to the Company.  The Intern will be presenting his/her results at laboratory operational meetings on a weekly basis.

Required and desired qualifications/experience: 

• A biomedical/ Chemical engineer background with some experience in biochemistry and/or biophysics.
• Some analytical background and/or expertise will be considered a plus.

Location:

You will be working in person at the MVT location: 1635 E 18th St, Tucson, Arizona 85719